Course aim: The overall goal of this course is for the students to gain a basic working knowledge of Pharmaceutical and Medicinal chemistry which involves the application of a number of specialized disciplinary approaches and all focused on the ultimate goal of drug discovery in both synthetic and natural products. This course covers the basic principles of drug design, drug target, identification and validation, rational (target-based) drug design, structural biology, methods development (chemical and biochemical), the techniques and approaches of chemical biology, synthetic organic chemistry, natural/herbal products and mechanistic enzymology.
Course ILOs: On successful completion of the course students should be able to:
• describe the history of medicines and the development up to date
• describe ADME process
• describe the structure of the drug to the ADME process
• explain the importance of stereochemistry of s drug and the use of receptors as sites of drug action
• explain the synthetic process of drug
• describe clinical trials